ioncube_loader_win_5.2.dll in the ionCube Loader 6.5 extension for PHP 5.2.4 does not follow safe_mode and disable_functions restrictions, which allows context-dependent attackers to bypass intended limitations, as demonstrated by reading arbitrary files via the ioncube_read_file function.
https://www.exploit-db.com/exploits/4517
https://exchange.xforce.ibmcloud.com/vulnerabilities/37227
http://www.securityfocus.com/bid/26024