Memory safety bugs were reported in Thunderbird 45.5. Some of these bugs showed evidence of memory corruption and we presume that with enough effort that some of these could be exploited to run arbitrary code. This vulnerability affects Firefox < 50.1, Firefox ESR < 45.6, and Thunderbird < 45.6.
https://www.mozilla.org/security/advisories/mfsa2016-96/
https://www.mozilla.org/security/advisories/mfsa2016-95/
https://www.mozilla.org/security/advisories/mfsa2016-94/
https://www.debian.org/security/2017/dsa-3757
https://security.gentoo.org/glsa/201701-15
http://www.securitytracker.com/id/1037461
http://www.securityfocus.com/bid/94885