In F5 BIG-IP LTM, AAM, AFM, Analytics, APM, ASM, DNS, GTM, Link Controller, PEM and Websafe software version 13.0.0, 12.0.0 to 12.1.2, 11.6.0 to 11.6.1 and 11.5.0 - 11.5.4, an undisclosed sequence of packets sent to BIG-IP High Availability state mirror listeners (primary and/or secondary IP) may cause TMM to restart.
https://support.f5.com/csp/article/K12044607