Node.js before 10.24.0, 12.21.0, 14.16.0, and 15.10.0 is vulnerable to a denial of service attack when too many connection attempts with an 'unknownProtocol' are established. This leads to a leak of file descriptors. If a file descriptor limit is configured on the system, then the server is unable to accept new connections and prevent the process also from opening, e.g. a file. If no file descriptor limit is configured, then this lead to an excessive memory usage and cause the system to run out of memory.
https://www.oracle.com/security-alerts/cpuoct2021.html
https://www.oracle.com/security-alerts/cpuApr2021.html
https://www.oracle.com//security-alerts/cpujul2021.html
https://security.netapp.com/advisory/ntap-20210416-0001/
https://nodejs.org/en/blog/vulnerability/february-2021-security-releases/
https://hackerone.com/reports/1043360
https://cert-portal.siemens.com/productcert/pdf/ssa-389290.pdf