XScreenSaver 5.45 can be bypassed if the machine has more than ten disconnectable video outputs. A buffer overflow in update_screen_layout() allows an attacker to bypass the standard screen lock authentication mechanism by crashing XScreenSaver. The attacker must physically disconnect many video outputs.
https://www.openwall.com/lists/oss-security/2021/06/05/1
https://github.com/QubesOS/qubes-xscreensaver/blob/master/0001-Fix-updating-outputs-info.patch
https://github.com/QubesOS/qubes-secpack/blob/master/QSBs/qsb-068-2021.txt
https://github.com/QubesOS/qubes-issues/issues/6595