SQLAlchemyDA is a generic database adapter for ZSQL methods. A vulnerability found in versions prior to 2.2 allows unauthenticated execution of arbitrary SQL statements on the database to which the SQLAlchemyDA instance is connected. All users are affected. The problem has been patched in version 2.2. There is no workaround for the problem.
https://github.com/zopefoundation/Products.SQLAlchemyDA/security/advisories/GHSA-r3jc-3qmm-w3pw